Oxidative stress test profiles cattle for diseases

OXIS International, Inc. has profiled the health status of more than 4,000 head of feedlot cattle in the U.S. over the last 18 months. Currently the Portland, OR-based company's clinical studies show a high correlation between oxidative stress values (OSV) exhibited by cattle and the onset of disease.

The unique OSV blood tests should enable cattlemen to quickly and cost-effectively identify susceptibility of cattle to various disease conditions such as bovine respiratory disease (BRD), which is estimated to cost the cattle industry more than $1 billion annually.

“The animal health profiling program assists our clients to better recognize disease in general, which keeps our food supply safer,” says Bruce Hoffman, DVM, Churchill, MT, director of OXIS Animal Health Profiling Programs.

OXIS believes it's the only company to offer a profile that provides a valuable analytical tool for managing the health of cattle. Using this profiling approach, cattle can be evaluated ranging from high risk to low risk for likelihood of disease. The feedlot can then manage high-risk cattle to assure early treatment is provided, and likely reduce labor and treatment for lower risk groups in the herd.

Studies show a statistically significant correlation between cattle with high OSV screening results when entering the feedlots and those ultimately pulled by the pen riders. Equally important, animals with high OSV levels were more likely to be pulled multiple times.

Also directly correlated to OXIS OSV levels was the carcass weight of cattle at slaughter. The higher the OSV levels exhibited by cattle in feedlots, the lower the carcass weight with resultant lower economic value of the animals sold.

Over the course of the entire feeding period of the study, cattle with lower OSVs achieved higher average daily weight gains. Also of economic importance were the correlations between elevated OSV levels among the cattle studied and the degree of respiratory death loss.

“OXIS is committed to animal health and consumer safety,” explains Ray Rogers, president and CEO of OXIS. “By profiling young animals and identifying high risk animals before slaughter, we believe we offer a valuable tool that enhances the safety of our food supply.”

OXIS also plans to initiate studies to assess the potential predictive value of its profiling system for bovine spongiform encephalopathy. The company holds the rights to three therapeutic classes of compounds in the area of oxidative stress, and develops, manufactures and markets products and technologies to diagnose and treat diseases caused by oxidative stress.

For additional information regarding the OXIS Animal Health Profiling Program call 503/452-7621.

Ag Employee Management

Kansas State and Oklahoma State universities are teaming up to present the 4th Employee Management for Production Agriculture Conference, Aug. 12-13.

“This is perhaps the leading agricultural labor management event in the country,” says Sarah Fogleman. She's the area Extension agricultural economist in southeast Kansas. “Past conferences have drawn large audiences from throughout the U.S. Representatives of everything from feedlots to swine operations to horticultural businesses to farms have participated.”

For more information or to register, visit the conference Web site at www.oznet.ksu.edu/employee or e-mail sfoglema@oznet.ksu.edu, or call 620/431-1530.