Feedyard Study From Merial

Large-scale feedyard study finds IVOMEC® (ivermectin) 1% Injection alone works as well as two other parasite control products combined

DULUTH, GA — July 11, 2008 — Cattle treated with IVOMEC® (ivermectin) 1% Injection perform just as well as cattle treated with both SAFE-GUARD® (fenbendazole) 10% Suspension and an ivermectin pour-on. That was the conclusion of a recent study conducted with a large group of feedyard cattle in Nebraska.1

The study in Nebraska followed more than 12,000 head of cattle from the time they entered the feedyard until close out. These animals came from a wide variety of sources and lived under normal commercial feedyard conditions. The parasite treatment regimens they received were randomly assigned.

The results showed conclusively that there was no difference in average in-weight, daily gain, out-weight, hot carcass weight or yield grade between the cattle treated with both SAFE-GUARD 10% Suspension and an ivermectin pour-on, and the group treated with IVOMEC 1% Injection alone.

“Both groups of cattle performed equally well. Statistically speaking, even in this extensive study, there was no difference between them,” says Dr. James Hawkins, Parasitologist and Consultant for Merial Veterinary Services. “Given these conclusions, there is really no reason to pay for — and devote the time and labor to using — two different products to do the work of one product.”

An earlier study, based on a smaller trial of 1,106 head, had suggested a possible benefit in gain and feed efficiency associated with using both SAFE-GUARD and an ivermectin pour-on.2 Dr. Hawkins says this limited data caused some to consider using two different products. But these latest results, which are based on a larger group of animals, demonstrate there is no advantage to accommodating the extra expense and labor of using two dewormers.

“There are advantages, however, to the use of parasite control in feedyards. These days, most feedyards are seeing profit margins shrink or even disappear. They have to scrutinize every expenditure. These results are good news for them,” Dr. Hawkins says. “And, because it is injectable, IVOMEC 1% Injection makes administering effective parasite control easy. It provides precise dosage in a convenient form.”

IVOMEC is the only family of parasite control products that offers four different, proven formulations to meet producers’ needs, and each one is backed by a satisfaction guarantee. IVOMEC 1% Injection was introduced in 1984; it is the original branded ivermectin product. According to market research from Merial, it is still the most trusted brand for protection from both internal and external parasites.3

Dr. Hawkins says that parasite control with IVOMEC 1% Injection can help feedyard cattle be more productive and gain weight more efficiently.

“It takes less than a pound of gain a day to pay the difference between IVOMEC 1% Injection and a generic ivermectin pour-on,” he explains. “If you add on the cost of a second product, too, it just doesn’t make economic sense.”

For more information, contact your local Merial Sales Representative or call 1-888-MERIAL-1.

IVOMEC Plus (ivermectin/clorsulon): Do not treat cattle within 49 days of slaughter. Do not use in dairy cattle of breeding age or in veal calves. IVOMEC (ivermectin) Pour-On: Do not treat cattle within 48 days of slaughter. Do not use in dairy cattle of breeding age or in veal calves. IVOMEC 1% Injection for Cattle and Swine: Do not treat cattle within 35 days of slaughter. Do not use in dairy cattle of breeding age or in veal calves. Do not treat swine within 18 days of slaughter. IVOMEC EPRINEX® (eprinomectin) Pour-On for Beef and Dairy: No meat or milk withdrawal is required when used according to label. All IVOMEC Brand Products: Do not use in other animal species not on the label as severe adverse reactions, including fatalities in dogs, may result.

Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products to enhance the health, well-being and performance of a wide range of animals. Merial employs more than 5,000 people and operates in more than 150 countries worldwide. Its 2007 sales were nearly $2.5 billion. Merial Limited is a joint venture between Merck & Co., Inc. and sanofi-aventis. For more information, please see www.merial.com.

CONTACT: Natasha Joseph

Merial

(678) 638-3690

natasha.joseph@merial.com

Wendy Mayo

Bader Rutter & Assoc.

(402) 434-5307

wmayo@bader-rutter.com

###

1Data on file at Merial.

2New data on SAFE-GUARD (fenbendazole) for pasture and feedlot cattle. Intervet Technical Bulletin-Part No. BV-SG00001.

3IVOMEC Brand Equity Study (Wood Mackenzie, April 2005).

®IVOMEC and EPRINEX are registered trademarks of Merial.

®SAFE-GUARD is a registered trademark of Intervet, Inc.

©2008 Merial Limited. Duluth, GA. All rights reserved. LAGEEGN828

Merial

3239 Satellite Blvd.

Duluth, GA 30096

www.merial.com

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